Polavarapu Lab

Welcome to the website of Dr Kiran Polavarapu’s research group in Ottawa, Canada. These pages are maintained by group members to provide an overview of our research and clinical activities.

We focus on scientific and genetic research into rare neuromuscular disorders. We aim to understand why small variations in the human genome lead to these frequently disabling, sometimes lethal, and rarely treatable conditions affecting the musculature and nervous system. Our group aims to identify the underlying genetic defects in patients using deep phenotyping and next-generation sequencing, and in collaboration with basic science groups worldwide, unravel molecular pathways in cell and animal models.

Kiran is affiliated with the CHEO Research Institute’s Biology Breakthrough Team and the Department of Cellular and Molecular Medicine at the University of Ottawa. He has close collaborations with many other research groups across the world.